Heparin-induced thrombocytopenia: laboratory studies.

Heparin induced thrombocytopenia

Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...

Laboratory diagnosis of heparin-induced thrombocytopenia and monitoring of alternative anticoagulants.

بروز ترومبوسیتوپنی ناشی ازهپارین، در دو روش تجویز داخل وریدی در بیماران با سندرم حاد کرونری

  Incidence of Thrombocytopenia Induced by Two Methods of Intravenous Heparin injection in Patients with Acute Coronary Syndrome.     H. Nough MD1* , A. Khodadadi Zadeh MSc2, M. Aref 3, A. Esmaieli ‌ Nadimi MD1     1- Assisstant Professor of Cardiology, University of Medical Sciences, Rafsanjan, Iran   2- Academic Member, Dept. of Nursing, Faculty of Nursing Midwifery, University of Medical Sci...

Diagnosis and management of heparin-induced thrombocytopenia.

PURPOSE To review recent developments in the pathogenesis, clinical features, laboratory testing and treatment of heparin-induced thrombocytopenia (HIT). METHODS Narrative review of the literature, including relevant papers published in English or French. PRINCIPAL FINDINGS Although the prevalence of HIT has decreased with the widespread use of low molecular weight heparin in the past ten y...

Laboratory tests for the diagnosis of heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia (HIT) is associated with high morbidity and mortality. Because the pathophysiology of this complex disorder has remained unclear, so has the development of supportive diagnostic laboratory assays. The currently available laboratory methods for HIT diagnosis include several platelet function assays: the platelet aggregation assay, platelet aggregation with simult...